|
|
| |
Gastrointestinal Dysfunction Symptoms and Lipids Profile in Patients with Various Severities of Acne Vulgaris |
|
Heidarali Esmaeili,
Monireh Halimi and Amir Hagigi |
Abstract:
According to an old notion, the axis of “brain-gut-skin” plays a
significant role in the pathogenesis of acne vulgaris. This study aimed to compare
gastrointestinal dysfunction symptoms in patients with different severities
of acne vulgaris with their normal counterparts. In this cross-sectional, case-control
study, 120 adolescents and young adults were recruited from two teaching dermatological
clinics over a one-year period (2012-2013). These participants were 30 normal
subjects (controls), 30 patients with mild acne vulgaris, 30 patients with moderate
acne vulgaris and 30 patients with severe acne vulgaris. Frequency of gastrointestinal
dysfunction symptoms including halitosis, gastric reflux, abdominal bloating,
abdominal discomfort, constipation and diarrhea was compared between the controls
and the patients. Serum lipids profile was also compared between the patients
and the controls. All the four studied groups were matched for their members’
age and sex. Controls and the cases with mild acne vulgaris were comparable
in terms of the frequency of gastrointestinal symptoms. Frequencies of abdominal
bloating (30% vs. 10%, p = 0.05) and constipation (36.7% vs. 13.3%, p = 0.04)
were significantly higher in the group with moderate acne comparing with the
controls. They were also significant more frequent in the patients with severe
acne comparing with the controls (40%, p = 0.01 and 46.7%, p = 0.01, respectively).
Comparing with the controls, serum lipids profile was significantly deranged
only in the cases with severe acne vulgaris. This study showed that gastrointestinal
dysfunction is associated with moderate-to-sever acne vulgaris. In addition,
serum lipids profile may be abnormal only in severe acne vulgaris.
|
|
|
PDF
Fulltext
XML
References
Citation
Report Citation
|
|
|
|
| RELATED ARTICLES: |
|
|
|
|
|
|
|
How to cite this article:
Heidarali Esmaeili, Monireh Halimi and Amir Hagigi, 2014. Gastrointestinal Dysfunction Symptoms and Lipids Profile in Patients with Various Severities of Acne Vulgaris. Journal of Medical Sciences, 14: 130-136.
DOI: 10.3923/jms.2014.130.136
URL: https://scialert.net/abstract/?doi=jms.2014.130.136
|
|
|
|
|
| COMMENT ON THIS PAPER |
|
|
|
|
| |
 |
Navigation |
| |
|
|
| |
|
Indexed In |
| |
|
|
Subscribe Today 
