Avian/Bird Flu Virus: Poultry Pathogen Having Zoonotic and Pandemic Threats: A Review


	Journal of Medical Sciences
	Year: 2013 \| Volume: 13 \| Issue: 5 \| Page No.: 301-315 DOI: 10.3923/jms.2013.301.315

Avian/Bird Flu Virus: Poultry Pathogen Having Zoonotic and Pandemic Threats: A Review

Kuldeep Dhama, Sandip Chakraborty, Ruchi Tiwari, Amit Kumar, Anu Rahal, Shyma K. Latheef, Mohd Yaqoob Wani and Sanjay Kapoor

Abstract: Avian/Bird flu, caused by Avian Influenza Virus (AIV) belonging to Orthomyxoviridae family, is the most fearful viral disease of birds. H5N1 subtype of AIV is of major concern for poultry as well as for humans due to its high economical impacts and zoonotic concerns. During the past ten years, the Highly Pathogenic Avian Influenza (HPAI) H5N1 subtype alone has affected more than 60 countries of the world. Domestic poultry is mostly affected by the disease episodes and outbreaks. Wild and migratory birds are the AIV reservoirs wherein H5N1 is found to be lethal. Major antigenic changes in Haemagglutinin (HA) or Neuraminidase (NA) result in periodic pandemics. Pigs can act as mixing vessel. The bird flu virus if gets the capability of transmitting from human to human can trigger a pandemic claiming millions of lives. A wide variety of serological tests and molecular tools have greatly aided in the diagnosis of avian flu. Disease management for the prevention of bird flu outbreaks including mass awareness and pandemic preparedness following World Health Organization (WHO) guidelines is of utmost importance. Interesting approaches of HPAI control are development of universal influenza virus vaccines and universal antibodies-based flu therapies. Vaccination using inactivated and recombinant vaccines is the common strategy adopted in different parts of the globe. Development of new generation vaccines is quiet noteworthy. Tamiflu is the drug of choice. Herbal therapy is gaining much attention to control disease in humans. All these aspects of the bird flu virus have been discussed vividly in the present review.

PDF Fulltext XML References Citation Report Citation

RELATED ARTICLES:

•	Artificial Insemination in Poultry and Possible Transmission of Infectious Pathogens: A Review

•	Emergence of Avian Infectious Bronchitis Virus and its Variants Need Better Diagnosis, Prevention and Control Strategies: A Global Perspective

•	Glanders-A Re-emerging Zoonotic Disease: A Review

•	Pathogens Transmitted by Migratory Birds: Threat Perceptions to Poultry Health and Production

How to cite this article:

Kuldeep Dhama, Sandip Chakraborty, Ruchi Tiwari, Amit Kumar, Anu Rahal, Shyma K. Latheef, Mohd Yaqoob Wani and Sanjay Kapoor, 2013. Avian/Bird Flu Virus: Poultry Pathogen Having Zoonotic and Pandemic Threats: A Review. Journal of Medical Sciences, 13: 301-315.

DOI: 10.3923/jms.2013.301.315

URL: https://scialert.net/abstract/?doi=jms.2013.301.315

COMMENT ON THIS PAPER

Navigation


		Online First
		Current Issue
		Previous Issues
		Editorial Board
		Submit a Manuscript
		Guide to Authors
		Subscribe to E-alerts

Indexed In


		ASCI-Database
		Asian Digital Library
		EMBASE
		Google Scholar
		SCIMAGO

Follow @scialert

Science Alert