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Journal of Medical Sciences
  Year: 2007 | Volume: 7 | Issue: 3 | Page No.: 481-484
DOI: 10.3923/jms.2007.481.484
 
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The Efficacy of L-arginine Gel for Treatment of Chronic Anal Fissure Compared to Surgical Sphincterotomy

Fariborz Eshghi

Abstract:
Aim of the present study was to compare the effect of L-arginine (chemical sphinctrotomy) with lateral internal sphinctrotomy (surgical sphinctrotomy) in treatment of chronic anal fissure. This clinical trial study was preformed on 60 patients referring to hospital complaining of chronic anal fissure diseases. They were randomized two groups of equal number patients undergoing internal sphinctrotomy (control) and treatment of topical L-arginine gel (case). All of the patients were assessed for pain, bleeding and wound healing for three months. The results obtained from case group showed that rectal bleeding discontinued and pain controlled in 70% while wound healing occurred in only 26.7%. In the control group treated with surgical method, had not any pain and bleeding after treatment and wound healing occurred in 56.7%. Local application of L-arginine cannot use instead to surgical internal sphinctrotomy, but can be used when patient is not candidate for surgery and predisposing complication.
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How to cite this article:

Fariborz Eshghi , 2007. The Efficacy of L-arginine Gel for Treatment of Chronic Anal Fissure Compared to Surgical Sphincterotomy. Journal of Medical Sciences, 7: 481-484.

DOI: 10.3923/jms.2007.481.484

URL: https://scialert.net/abstract/?doi=jms.2007.481.484

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