Submit Manuscript

Research Journal of Microbiology

Year: 2014 | Volume: 9 | Issue: 1 | Page No.: 25-33
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend

Total views 559

Search

Authors

S. Manikandan

S. Ganesapandian

N. Sangeetha

A.K. Kumaraguru

Keywords

Research Article

Antimicrobial Activity of Marine Sponges Associated some Marine Bacterial Metabolites Against Multi Drug Resistance Human Pathogens

S. Manikandan, S. Ganesapandian, N. Sangeetha and A.K. Kumaraguru
Marine bacteria are producers of secondary metabolites in the harsh ocean. In the present study, marine bacteria were isolated from marine sponges in the Gulf of Mannar. The potential isolates were selected for 16S rRNA gene sequencing. The results of phylogenetic analyses revealed that isolate No. 3 was Stenotrophomonas sp., strain SMAKK001; isolate No. 6 was Bacillus strain SMAKK002 and isolate No. 8 was identified as Bacillus sp. strain SMAKK003. Antimicrobial assays were performed against various microorganisms with bacterial metabolites. Out of the 10 marine bacterial filtrates only four filtrates exhibited antimicrobial activity. Among them, the filtrate of Stenotrophomonas sp. strain SMAKK001, Bacillus subtilis strain SMAKK002 exhibited strong activity against gram positive and negative bacterial strains. Secondary metabolite of marine bacterial isolates SMAKK001, SMAKK002 and SMAKK003 showed considerable inhibitory activity against pathogenic bacteria and fungi. Inhibitory activity was observed against important pathogenic species such as MDR Staphylococcus sp., MDR Pseudomonas sp. and MDR Klebsiella sp. which opens up interesting avenues in the search for novel compounds against multidrug-resistant pathogenic bacteria. The present study revealed that marine bacterial metabolites used against potential new anti-MDR strains.
PDF Fulltext XML References Citation

How to cite this article

S. Manikandan, S. Ganesapandian, N. Sangeetha and A.K. Kumaraguru, 2014. Antimicrobial Activity of Marine Sponges Associated some Marine Bacterial Metabolites Against Multi Drug Resistance Human Pathogens. Research Journal of Microbiology, 9: 25-33.

URL: https://scialert.net/abstract/?doi=jm.2014.25.33

Leave a Comment

Your email address will not be published. Required fields are marked *