Research Article

**Niromycin A: An Antialgal Substance Produced by Streptomyces endus N40**

S.A. El-Shirbiny, M.F. Ghaly, Y.M. El-Ayoty and N.S. Fleafil

The antialgal activity of 107 Actinomycete isolates were isolated from different localities in El-Sharkia, El-Dakahliya and El-Meniya governorates. Egypt. Isolate No. 40 (isolated from Ekhtab. Aga, Dakahliya) was selected and identified as Streptomyces endus N40. The optimum culture conditions for the production of the antialgal metabolite were studied. It has been found that the optimum incubation temperature for the production of the antialgal metabolite from Streptomyces endus N40 was 28°C after incubation period (8 days) at pH 6.5. The most favorable carbon, nitrogen, phosphorus, microelement and vitamin sources were maltose (6 g L^-1), asparagine (1.486 g L^-1), K₂HPO₄ (I g L^-1), FeSO₄.7H₂O (0.01 g L^-1) and (inositol) (0.01 mg L^-1), respectively. The maximum antialgal activity was obtained against Anabaena sp. Anabaena flos-aqueae, Nostoc sp. and Anacystis nidulans. The antialgal substance had extracted using xylene solvent Formulation and identification of the antialgal substance that produced by Streptomyces endus N40 was carrying out using IR, Mass, NMR spectra and elementary analysis and these results were emphasized that the molecular weight equal 279.33 KDa with chemical formula (C₁₅H₂₁NO₄) and identified as Niromycin A.

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S.A. El-Shirbiny, M.F. Ghaly, Y.M. El-Ayoty and N.S. Fleafil, 2007. Niromycin A: An Antialgal Substance Produced by Streptomyces endus N40. Research Journal of Microbiology, 2: 606-618.

URL: https://scialert.net/abstract/?doi=jm.2007.606.618

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Authors

S.A. El-Shirbiny

M.F. Ghaly

Y.M. El-Ayoty

N.S. Fleafil

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Research Article

**Niromycin A: An Antialgal Substance Produced by Streptomyces endus N40**

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