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Journal of Fisheries and Aquatic Science

Year: 2018 | Volume: 13 | Issue: 1 | Page No.: 49-55
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Authors

Basel Saleh

Basel Saleh

Ayman Al-Mariri

Keywords

Research Article

Antifungal Activity of Crude Seaweed Extracts Collected from Lattakia Coast, Syria

Basel Saleh Basel Saleh's LiveDNA and Ayman Al-Mariri
Background and Objective: Seaweed extracts displayed a broad spectrum as antimicrobial agent due to their richness in bioactive compounds. Seven seaweeds [Codium tomentosum (Chlorophyta), Corallina mediterranea, Hypnea musciformis and Laurencia papillosa (Rhodophyta) and Padina pavonica, Sargassum vulgare and Dictyota dichotoma (Phaeophyta)] crude extracts effectiveness had been evaluated against two fungal (Aspergillus niger and Candida albicans) strains using aqueous, methanol, ethanol, chloroform, acetone, ethyl acetate and hexane solvents. Materials and Methods: Seaweeds antifungal effect had been evaluated based on the zone of inhibition (ZI), Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC). Amphotericin B (40 mg mL–1) was used as standard for antifungal activity. Results: Aqueous extracts showed no activity against the two tested fungi regardless examined seaweeds species. Whereas, the other six organic extracts adversely affected fungal strains. Overall, D. dichotoma showed no activity against the two tested fungi regardless examined solvents. Moreover, methanolic S. vulgare extract was the strongest by showing the lowest MIC value of 0.11 and 0.13 mg mL–1 against A. niger and C. albicans fungal strains, respectively and the lowest MFC value of 1.67 mg mL–1 for the both fungal strains. Conclusion: Seaweeds seem to be promising natural resources with low cost for antifungal treatment. Further researches on methanolic S. vulgare extracts fractions is requested.
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