Submit Manuscript

Journal of Biological Sciences

Year: 2011 | Volume: 11 | Issue: 1 | Page No.: 31-38
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend

Total views 245

Authors

Mindiediba Jean Bangou

Martin Kiendrebeogo

Moussa Compaore

Ahmed Yacouba Coulibaly

Nag-Tiero Roland Meda

Norma Almaraz Abarca

Boukare Zeba

Jeanne Millogo-Rasolodimby

Odile Germaine Nacoulma

Keywords

In the present study, 36 plant extracts, belonging to 6 families from Burkina Faso were used to evaluate their glutathione-S-transferase (GST), acetylcholinesterase (AChE), carboxylesterase (CES) and xanthine oxidase (XO) inhibitory activities and their phenolic, tannin and flavonoids contents by using spectrophotometrical methods. At 100 μg mL-1, Lippia chevalieri, Eclipta prostrata, Lantana camara and Indigofera pulchra extracts showed the best percentage of inhibition by regulating GST, AChE, CES and XO activities, respectively. The phytochemical investigations showed that all plant extracts were rich in biological compounds, namely phenolic, tannin and flavonoids. Particularly Cassia mimosoides extract presented the best phenolic, tannin and flavonoid contents. This result indicated that phenolic from Ceasalpiniaceae, flavonoids from Combretaceae and tannin from Verbenaceae contribute significantly to the inactivation of CES, AchE and GST, respectively. However, no significant correlation was found between polyphenolic compounds content and XO inhibitory activity. Present findings could partially justify the traditional uses of these plants in the treatment of mental disorders, gout, painful inflammations and cardiovascular diseases.
PDF Fulltext XML References Citation

How to cite this article

Mindiediba Jean Bangou, Martin Kiendrebeogo, Moussa Compaore, Ahmed Yacouba Coulibaly, Nag-Tiero Roland Meda, Norma Almaraz Abarca, Boukare Zeba, Jeanne Millogo-Rasolodimby and Odile Germaine Nacoulma, 2011. Enzyme Inhibition Effect and Polyphenolic Content of Medicinal Plant Extracts from Burkina Faso. Journal of Biological Sciences, 11: 31-38.

DOI: 10.3923/jbs.2011.31.38

URL: https://scialert.net/abstract/?doi=jbs.2011.31.38

Related Articles

Effects of Organic Extracts of Bursera copallifera and B. lancifolia Leaves in the Development of Spodoptera frugiperda
Anti Sickle Erythrocytes Haemolysis Properties and Inhibitory Effect of Anthocyanins Extracts of Trema orientalis (Ulmaceae) on the Aggregation of Human Deoxyhemoglobin S in vitro
Terminalia arjuna (Roxb.) Wt. and Arn. : A Review
In vitro Inhibition of Acetylcholinesterase, Butyrylxcholinesterase and Lipoxygenase by Crude Extract of Myricaria elegans Royle
Indonesian Sidaguri (Sida rhombifolia L.) as Antigout and Inhibition Kinetics of Flavonoids Crude Extract on the Activity of Xanthine Oxidase
Polyphenol Contents and Antioxidant Activities of Five Indigofera Species (Fabaceae) from Burkina Faso
Anticancer Activity Test for Extracts of Sarang Semut Plant (Myrmecodya pendens) to HeLa and MCM-B2 Cells

Leave a Comment

Your email address will not be published. Required fields are marked *