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Journal of Biological Sciences
  Year: 2004 | Volume: 4 | Issue: 6 | Page No.: 763-767
DOI: 10.3923/jbs.2004.763.767
 
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In vitro Toxicity of Ethanolic Plant Extracts from Adamawa Province, Cameroon to Infective Larvae of Strongyloides papillosus

G. Musongong , E.N. Nukenine , M. Ngassoum , T. Gangue , O. Messine , C.N. Fokunang , F.G. Zalom , L.M. Njongmeta and V. Tanya

Abstract:
Ethanolic leaf extracts from five herbal plants (Annona senegalensis, Lantana camara, Steganotaenia araliacea, Vernonia amygdalina and Vernonia tonoreana), collected in the Adamawa Province of Cameroon, were assessed for toxicity against the infective larval stage (third-instar) of Strongyloides papillosus (Weedl), for post-exposure periods ranging from 1-48 h. Acute toxicity at 24 and 48 h post-exposure were also determined. Larval mortality increased over time for all of the herbal extracts at all concentration levels. A maximum 100% mortality at 48 h post-exposure was recorded only for A. senegalensis. LC50 values recorded at 48 h post exposure were A. senegalensis (0.100%), V. tonoreana (0.107%), S. araliacea (0.183%), V. amygdalina (0.203) and L. camara (0.496%). High acute toxicity was recorded for A. senegalensis, V. tonoreana and S. araliace, suggesting these plants could yield natural alternative treatment products for S. papillosus.
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How to cite this article:

G. Musongong , E.N. Nukenine , M. Ngassoum , T. Gangue , O. Messine , C.N. Fokunang , F.G. Zalom , L.M. Njongmeta and V. Tanya , 2004. In vitro Toxicity of Ethanolic Plant Extracts from Adamawa Province, Cameroon to Infective Larvae of Strongyloides papillosus. Journal of Biological Sciences, 4: 763-767.

DOI: 10.3923/jbs.2004.763.767

URL: https://scialert.net/abstract/?doi=jbs.2004.763.767

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