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Journal of Applied Sciences
  Year: 2007 | Volume: 7 | Issue: 17 | Page No.: 2485-2489
DOI: 10.3923/jas.2007.2485.2489
 
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Antimicrobial Activity and Synthesis of Quinoline-Based Chalcones

Muhammad Azad, Munawar Ali Munawar and Hamid Latif Siddiqui

Abstract:
A series of quinoline-based chalcones have been prepared by the condensation of quinoline-3-carbaldehydes with acetophenone and N-substituted-3-acetyl-4-hydroxy-2-quinolones with heterocyclic carbaldehydes. The prepared chalcones have been screened for antimicrobial activities against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtiles, Klebsiellea erogeues, Staphylococcus albus, Aspergillus flavus, Aspergillus niger, Rhodolorula rubera, Lipomyces lopofera and Candida albicans. All the prepared chalcones have shown significant antimicrobial activities.
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How to cite this article:

Muhammad Azad, Munawar Ali Munawar and Hamid Latif Siddiqui , 2007. Antimicrobial Activity and Synthesis of Quinoline-Based Chalcones. Journal of Applied Sciences, 7: 2485-2489.

DOI: 10.3923/jas.2007.2485.2489

URL: https://scialert.net/abstract/?doi=jas.2007.2485.2489

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