• [email protected]
  • +971 507 888 742
Submit Manuscript
SciAlert
  • Home
  • Journals
  • Information
    • For Authors
    • For Referees
    • For Librarian
    • For Societies
  • Contact
  1. International Journal of Pharmacology
  2. Vol 11 (2), 2015
  3. 76-94
  • Online First
  • Current Issue
  • Previous Issues
  • More Information
    Aims and Scope Editorial Board Guide to Authors Article Processing Charges
    Submit a Manuscript

International Journal of Pharmacology

Year: 2015 | Volume: 11 | Issue: 2 | Page No.: 76-94
DOI: 10.3923/ijp.2015.76.94

Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend



Total views 684

Search


Authors


K. Dhama

Country: India

M. Kesavan

Country: India

K. Karthik

Country: India

Amarpal

Country: India

R. Tiwari

Country: India

Lakshmi T. Sunkara

Country: USA

R.K. Singh

Country: India

Keywords


  • vitamins
  • neuroimmunomodulators
  • neuronal cellular interactions
  • neuroimmune cross talk
  • stress
  • aging
  • infections
  • diseases
  • neural immunity
  • disorders
  • Neuroimmunomodulation
  • minerals
Review Article

Neuroimmunomodulation Countering Various Diseases, Disorders, Infections, Stress and Aging

K. Dhama, M. Kesavan, K. Karthik, Amarpal, R. Tiwari, Lakshmi T. Sunkara and R.K. Singh
Neuroimmunomodulation involves interactions among nervous, endocrine and immune systems. An integrated function is performed by nervous and immune systems that is responsible for preservation of integrity and homeostasis of the organism. Though Central Nervous System (CNS) has a limited repertoire for its own protection, it has the Blood Brain Barrier (BBB) and the capacity to engage peripheral immune system to eliminate infections and xenobiotics. Neural cells involved in the process of providing neural immunity include: Glial cells, astrocytes and oligodendrocytes. Besides working as sentinels to get rid of pathogens in the process of neurodevelopment, both central as well as peripheral immune cells actively participate helping in cognitive brain functions. Neurogenesis process may also be regulated by adaptive immune cells peripherally. Recently there is a discovery of cholinergic anti-inflammatory pathway wherein vagal nerve has shown anti-inflammatory role in endotoxemia and shock. Hormones viz., nor-epinephrine, epinephrine and glucocorticoids prepare immune system to combat infections and enhance distribution and trafficking of immune cells by several ways. This review focuses on neurobiology, neuro-immune cross talk, neuroimmunoregulation, stress and neuroimmunomodulation which will be beneficial for researchers, professionals and academicians. Topics like neurotoxic and neuroprotective roles of immune reactions (which are innate in nature) in the process of aging are highly debated among researchers. In this review, topics like neuroinflammation and neurodegeneration, role of vitamins, minerals, herbs and drugs and volatile oils in the process of neuroimmunomodulation and particularly countering various diseases, disorders, infections, stress and aging have been discussed vividly to enhance and update the knowledge of the scientific community regarding this particular topic ‘Neuroimmunomodulation’.
PDF Fulltext XML References Citation

How to cite this article

K. Dhama, M. Kesavan, K. Karthik, Amarpal, R. Tiwari, Lakshmi T. Sunkara and R.K. Singh, 2015. Neuroimmunomodulation Countering Various Diseases, Disorders, Infections, Stress and Aging. International Journal of Pharmacology, 11: 76-94.

DOI: 10.3923/ijp.2015.76.94

URL: https://scialert.net/abstract/?doi=ijp.2015.76.94

Related Articles

Novel and Emerging Therapies Safeguarding Health of Humans and Their Companion Animals: A Review
Immunomodulatory and Therapeutic Potentials of Herbal, Traditional/Indigenous and Ethnoveterinary Medicines
Nutraceuticals from Fruits and Vegetables at a Glance: A Review
Phytonutrients and Nutraceuticals in Vegetables and Their Multi-dimensional Medicinal and Health Benefits for Humans and Their Companion Animals: A Review

Leave a Comment


Your email address will not be published. Required fields are marked *

Useful Links

  • Journals
  • For Authors
  • For Referees
  • For Librarian
  • For Socities

Contact Us

Office Number 1128,
Tamani Arts Building,
Business Bay,
Deira, Dubai, UAE

Phone: +971 507 888 742
Email: [email protected]

About Science Alert

Science Alert is a technology platform and service provider for scholarly publishers, helping them to publish and distribute their content online. We provide a range of services, including hosting, design, and digital marketing, as well as analytics and other tools to help publishers understand their audience and optimize their content. Science Alert works with a wide variety of publishers, including academic societies, universities, and commercial publishers.

Follow Us
© Copyright Science Alert. All Rights Reserved