• [email protected]
  • +971 507 888 742
Submit Manuscript
SciAlert
  • Home
  • Journals
  • Information
    • For Authors
    • For Referees
    • For Librarian
    • For Societies
  • Contact
  1. International Journal of Pharmacology
  2. Vol 11 (5), 2015
  3. 496-501
  • Online First
  • Current Issue
  • Previous Issues
  • More Information
    Aims and Scope Editorial Board Guide to Authors Article Processing Charges
    Submit a Manuscript

International Journal of Pharmacology

Year: 2015 | Volume: 11 | Issue: 5 | Page No.: 496-501
DOI: 10.3923/ijp.2015.496.501

Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend



Total views 163

Authors


Ali H. Bahkali

Country: Saudi Arabia

Abdallah M. Elgorban

Country: Saudi Arabia

Abd El-Rahim M.A. El- Samawaty

Country: Saudi Arabia

Huda-Mogren A. Almogren

Country: Saudi Arabia

Mohamed A. El- Metwally

Country: Egypt

Naif S. Al-Harbi

Country: Saudi Arabia

Keywords


  • Aspergillus niger
  • Nigella sativa
  • spore germination
  • essential oils
Research Article

In vitro Susceptibility of Clinical Aspergillus Species to Some Antifungal Agents

Ali H. Bahkali, Abdallah M. Elgorban, Abd El-Rahim M.A. El- Samawaty, Huda-Mogren A. Almogren, Mohamed A. El- Metwally and Naif S. Al-Harbi
Aspergillus species are regularly involved in human broncho-pulmonary diseases, mainly in immunocompromised patients. The essential oils extracted from three different plants were tested for their inhibitory effect on the growth of five pathogenic Aspergilli including Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Aspergillus versicolor and Aspergillus terreus which are pathogens with clinical importance. The results of the antimicrobial tests showed that the isolated essential oils inhibited the growth of Aspergillus species to varying degrees. The Ocimum basilicum oil completely inhibited the mycelial growth and spore germination of A. terreus and A. fumigatus at 200 and 250 ppm. In addition, this oil showed a very strong antifungal activity against the mycelial growth and spore germination of A. flavus and A. versicolor with 97.7, 97.5, 91.2 and 93.5%, respectively, when compared with control. The essential oil extracted from Eucalyptus globulus also exhibited significant antifungal activity against the Aspergillus species tested. This oil completely inhibited the mycelial growth and spore germination of A. fumigatus. Conversely, Nigella sativa oil exhibited moderate inhibitory activity against all the tested Aspergillus species. The present study supports the proposition that plant essential oils may have a role in both pharmaceutical and agricultural practices.
PDF Fulltext XML References Citation

How to cite this article

Ali H. Bahkali, Abdallah M. Elgorban, Abd El-Rahim M.A. El- Samawaty, Huda-Mogren A. Almogren, Mohamed A. El- Metwally and Naif S. Al-Harbi, 2015. In vitro Susceptibility of Clinical Aspergillus Species to Some Antifungal Agents. International Journal of Pharmacology, 11: 496-501.

DOI: 10.3923/ijp.2015.496.501

URL: https://scialert.net/abstract/?doi=ijp.2015.496.501

Related Articles

In vitro Antifungal Activity of Some Plant Essential Oils
Inhibitory Influence of Plant Extracts on Soil Borne Fungi Infecting Muskmelon (Cucumis melo L.)

Leave a Comment


Your email address will not be published. Required fields are marked *

Useful Links

  • Journals
  • For Authors
  • For Referees
  • For Librarian
  • For Socities

Contact Us

Office Number 1128,
Tamani Arts Building,
Business Bay,
Deira, Dubai, UAE

Phone: +971 507 888 742
Email: [email protected]

About Science Alert

Science Alert is a technology platform and service provider for scholarly publishers, helping them to publish and distribute their content online. We provide a range of services, including hosting, design, and digital marketing, as well as analytics and other tools to help publishers understand their audience and optimize their content. Science Alert works with a wide variety of publishers, including academic societies, universities, and commercial publishers.

Follow Us
© Copyright Science Alert. All Rights Reserved