
	International Journal of Pharmacology
	Year: 2014 \| Volume: 10 \| Issue: 8 \| Page No.: 461-469 DOI: 10.3923/ijp.2014.461.469

Antioxidant and Antimutagenic Potential of Seeds and Pods of Green Cardamom (Elettaria cardamomum)

Asma Saeed, Bushra Sultana, Farooq Anwar, Muhammad Mushtaq, Khalid M. Alkharfy and Anwarul-Hassan Gilani

Abstract: The present study reports the antioxidant and antimutaganic potential of the aqueous (30 and 70%) and acidified (0.5 and 1 N) methanolic extracts from seeds and pods of green cardamom (Elettaria cardamomum). The Total Phenolic Compounds (TPC) of extracts were determined by Follin-Ciocalteu reagent. Antioxidant activity of the extracts produced was evaluated by the measurements of 2, 2,-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and percentage inhibition of linoleic acid peroxidation method, whereas mutagenic and antimutagenic activities were assessed using Ames bacterial test. The TPC, scavenging of DPPH° and inhibition of linoleic acid were found to be 27.75-126.35 mg gallic acid equivalent g^-1 DW, 46-91% at 5 mg L^-1 of extract concentration and 34-83%, respectively. Furthermore, the extracts of seeds and pods of green cardamom showed strong antimutagenic potential against mutant strains S. typhimurium TA98 and S. typhimurium TA100 while none of the extract showed mutagenicity. The results of this study support that the extracts from cardamom seeds and pods can be explored as potential chemotherapeutic agents against cancer as well as for the pharmaceutical and nutraceutical applications.

PDF Fulltext XML References Citation Report Citation

RELATED ARTICLES:

•	Citrullus lanatus Extract Reverses Oxidative and Haematological Dysfunction in Carbon Tetrachloride Induced Liver Damaged Rats

•	Variation in Antioxidant Activity and Phenolic and Flavonoid Contents in the Flowers and Leaves of Ghaneri (Lantana camara L.) as Affected by Different Extraction Solven

•	A Systematic Review about Effects of Aerial Portions of Urtica dioica (Nettle) on Some Cardiovascular Risk Factors in Diabetes Mellitus

•	Antioxidants: Their Role in Health and Disease

How to cite this article:

Asma Saeed, Bushra Sultana, Farooq Anwar, Muhammad Mushtaq, Khalid M. Alkharfy and Anwarul-Hassan Gilani, 2014. Antioxidant and Antimutagenic Potential of Seeds and Pods of Green Cardamom (Elettaria cardamomum). International Journal of Pharmacology, 10: 461-469.

DOI: 10.3923/ijp.2014.461.469

URL: https://scialert.net/abstract/?doi=ijp.2014.461.469

COMMENT ON THIS PAPER

Navigation


		Online First
		Current Issue
		Previous Issues
		Editorial Board
		Submit a Manuscript
		Guide to Authors
		Subscribe to E-alerts

Indexed In


		ASCI-Database
		Asian Digital Library
		Chemical Abstract Services
		EMBASE
		Google Scholar
		ISI Web of Knowledge
		Science Citation Index (EXP)
		SCIMAGO
		Thomson ISI

Science Alert