
	International Journal of Pharmacology
	Year: 2006 \| Volume: 2 \| Issue: 4 \| Page No.: 426-430 DOI: 10.3923/ijp.2006.426.430

Liver Regenerative Effect of Phyllanthus amarus Linn. Against Alcohol Induced Liver Cell Injury in Partially Hepatectomised Albino Rats

P. Chattopadhyay , S.S. Agrawal and A. Garg

Abstract: The present study investigates the liver regenerative effect of Phyllathus amarus Linn against alcohol induced liver cell injury in partial hepatectomised albino rats. The oral administration of Phyllanthus amarus extracts increases the activities of thymidine kinase in regenerating rat liver at 24 h. Levels of DNA and protein analysis showed that the increase in thymidine kinase was caused by comparable increase the DNA and protein. Histopathology confirmed the mitosis counts increases to the activity of DNA. These findings suggested that Phyllanthus amarus inducing DNA synthesis by the induction of levels of synthesizing nucleic acid enzymes during liver regeneration. Phyllanthus amarus may be used, as a potential liver regenerative herb in hepatic disorders and seems to be beneficial against alcohol induced liver cell damage.

PDF References Citation Report Citation

RELATED ARTICLES:

•	Antidiabetic Activity of Phyllanthus amarus Schum and Thonn (Euphorbiaceae) on Alloxan Induced Diabetes in Male Wistar Rats

How to cite this article:

P. Chattopadhyay , S.S. Agrawal and A. Garg , 2006. Liver Regenerative Effect of Phyllanthus amarus Linn. Against Alcohol Induced Liver Cell Injury in Partially Hepatectomised Albino Rats. International Journal of Pharmacology, 2: 426-430.

DOI: 10.3923/ijp.2006.426.430

URL: https://scialert.net/abstract/?doi=ijp.2006.426.430

COMMENT ON THIS PAPER

Navigation


		Online First
		Current Issue
		Previous Issues
		Editorial Board
		Submit a Manuscript
		Guide to Authors
		Subscribe to E-alerts

Indexed In


		ASCI-Database
		Asian Digital Library
		Chemical Abstract Services
		EMBASE
		Google Scholar
		ISI Web of Knowledge
		Science Citation Index (EXP)
		SCIMAGO
		Thomson ISI

Science Alert