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International Journal of Dairy Science
  Year: 2011 | Volume: 6 | Issue: 3 | Page No.: 190-197
DOI: 10.3923/ijds.2011.190.197
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Beneficial Effect of Camel Milk on Liver and Kidneys Function in Diabetic Sprague-Dawley Rats

E.M. Hamad, E.A. Abdel-Rahim and E.A. Romeih

Recently, several studies demonstrated the potential health attributes of camel milk. The present study was designed to explore the effect of camel milk - compared to cow and buffalo milks on blood glucose and liver and kidneys function. Thirty male Sprague-Dawley rats were divided into five groups. For comparison, one group was used as a normal control, while the remaining four groups were injected with streptozotocin in order to induce diabetes. One of the diabetic groups were used as a Diabetic Control Group (DCG), whereas, three diabetic groups were fed on diets containing cow (COM), buffalo (BFG) or camel milks (CMG) for six weeks. Insulin content in camel milk (58.67±2.01 U L-1) was more than that of cow or buffalo milks (17.01±0.96 and 16.21±0.95 U L-1, respectively). Feeding diabetic rats on camel milk was showing a higher hypoglycemic effect (~49.2 %) than that of either COM or BFG (~11.6 and 11.1%, respectively) compared to the DCG group. Giving camel milk led to an improvement in activities of alanine amino-transferase and aspartate amino-transferase by 41 and 38%, respectively; compared to the DCG rats. A significant (p<0.05) reduction effects on uric acid, urea and creatinine levels were observed in the CMG, COG and BFG groups. The present work confirms the hypoglycemic effect of camel milk as well as marked improvements in liver and kidneys function, which was greater than those of COG and BFG groups. Indeed, extensive research on camel milk is still needed to identify the relevance components of these healthy functions.
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  •    Fermented Camel (Camelus dromedarius) and Bovine Milk Attenuate Azoxymethane-induced Colonic Aberrant Crypt Foci in Fischer 344 Rats
  •    Nephroprotective Effect of Camel Milk and Spirulina platensis in Gentamicin-Induced Nephrotoxicity in Rats
  •    Protective Effects of Camellia sinensis Leaf Extract against Carbon Tetrachloride-Induced Liver Injury in Rats
  •    Camel Milk Regulates Gene Expression and Activities of Hepatic Antioxidant Enzymes in Rats Intoxicated with Carbon Tetrachloride
  •    Effect of Murraya koenigii Leaf Extract on Carbohydrate Metabolism Studied in Streptozotocin Induced Diabetic Rats
  •    The Hypocholesterolemic Effect of Gariss and Gariss Containing Bifidobacteria in Rats Fed on a Cholesterol-Enriched Diet
  •    Prevention of Alloxan Induced Diabetes Mellitus in Rats by Vitamin a Dietary Supplementation
  •    Hepatoprotective Effects of Camel Milk against CCl4-induced Hepatotoxicity in Rats
How to cite this article:

E.M. Hamad, E.A. Abdel-Rahim and E.A. Romeih, 2011. Beneficial Effect of Camel Milk on Liver and Kidneys Function in Diabetic Sprague-Dawley Rats. International Journal of Dairy Science, 6: 190-197.

DOI: 10.3923/ijds.2011.190.197






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