• [email protected]
  • +971 507 888 742
Submit Manuscript
SciAlert
  • Home
  • Journals
  • Information
    • For Authors
    • For Referees
    • For Librarian
    • For Societies
  • Contact
  1. International Journal of Cancer Research
  2. Vol 8 (2), 2012
  3. 37-48
  • Online First
  • Current Issue
  • Previous Issues
  • More Information
    Aims and Scope Editorial Board Guide to Authors Article Processing Charges
    Submit a Manuscript

International Journal of Cancer Research

Year: 2012 | Volume: 8 | Issue: 2 | Page No.: 37-48
DOI: 10.3923/ijcr.2012.37.48

Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend



Total views 395

Search


Authors


Abdurrahman Al Diab

Country: Saudi Arabia

S. Qureshi

Country: Saudi Arabia

Mohammad Farhan Qureshi

Country: Saudi Arabia

Viquar Fatima Qureshi

Country: Saudi Arabia

Mohammad Rehan Qureshi

Country: India

Keywords


  • Colorectal cancer
  • established drugs
  • toxicities
  • herbal treatment
  • molecular targets
Mini Review

Experimental Approach to Treatment of Colorectal Cancer by Herbs and Their Constituents: An Overview on in vivo and in vitro Protocols and Molecular Targets

Abdurrahman Al Diab, S. Qureshi, Mohammad Farhan Qureshi, Viquar Fatima Qureshi and Mohammad Rehan Qureshi
Behind the alluring fame of established drugs in a magical cure of some types of cancers are myriad toxicities. Hence, it became imperative to search alternative approaches of treatment. Although a large number of papers are published to show that herbs, plant products and their constituents are capable to inhibit the growth of a variety of human colon carcinoma cell lines, there is a gross neglect on an impact of in vivo outcome which show overall effects. The present study on an experimental approach to treatment of Colorectal Cancer (CRC) by herbs, plant products and their constituents was undertaken to review the (1) adverse effects of established drugs used against CRC, (2) herbs, plant products and their constituents as alternatives to established drugs, (3) in vivo studies on herbs, plant products and their ingredients, (4) in vitro studies on herbs, plant products and their ingredients, (5) pros and cons of in vivo and in vitro studies, (6) molecular targets and (7) conclusion. The articles included were peer reviewed English language articles published up to November 2011. These were selected from Pub Med, Pub Med Central, Science Direct, Up-to-date, Med Line, Comprehensive databases, Cochrane library and the internet (Google, Yahoo). The search strategy corresponded with points, 1-6 above. The literature obtained is reviewed. It is suggested that the laboratories working on CRC with in vitro protocol may also undertake confirmatory in vivo experimentation with an application of gene expression profiling using microarray technologies.
PDF Fulltext XML References Citation

How to cite this article

Abdurrahman Al Diab, S. Qureshi, Mohammad Farhan Qureshi, Viquar Fatima Qureshi and Mohammad Rehan Qureshi, 2012. Experimental Approach to Treatment of Colorectal Cancer by Herbs and Their Constituents: An Overview on in vivo and in vitro Protocols and Molecular Targets. International Journal of Cancer Research, 8: 37-48.

DOI: 10.3923/ijcr.2012.37.48

URL: https://scialert.net/abstract/?doi=ijcr.2012.37.48

Related Articles

Cytotoxic Activity of Pereskia bleo (Cactaceae) Against Selected Human Cell Lines
Chemopreventive Potential of Bitter Melon (Momordica charantia) against Precancerous Lesions in the Colon of Fisher 344 Male Rats
Anticancer and Biochemical Effects of Calcium Chloride on Ehrlich Carcinoma Cell-Bearing Swiss Albino Mice
Anti-tumor Activity of Some 1,3,4-thiadiazoles and 1,2,4-triazine Derivatives against Ehrlichs Ascites Carcinoma
In vitro Antioxidant and Anti-neoplastic Activities of Ocimum sanctum Leaves in Ehrlich Ascites Carcinoma Bearing Mice

Leave a Comment


Your email address will not be published. Required fields are marked *

Useful Links

  • Journals
  • For Authors
  • For Referees
  • For Librarian
  • For Socities

Contact Us

Office Number 1128,
Tamani Arts Building,
Business Bay,
Deira, Dubai, UAE

Phone: +971 507 888 742
Email: [email protected]

About Science Alert

Science Alert is a technology platform and service provider for scholarly publishers, helping them to publish and distribute their content online. We provide a range of services, including hosting, design, and digital marketing, as well as analytics and other tools to help publishers understand their audience and optimize their content. Science Alert works with a wide variety of publishers, including academic societies, universities, and commercial publishers.

Follow Us
© Copyright Science Alert. All Rights Reserved