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International Journal of Biological Chemistry

Year: 2007 | Volume: 1 | Issue: 1 | Page No.: 38-46
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Authors

I.G. Adanlawo

F.A.S. Dairo

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Research Article

Nutrient and Anti-nutrient Constituents of Ginger (Zingiber officinale, Roscoe) and the Influence of its Ethanolic Extract on Some Serum Enzymes in Albino Rats

I.G. Adanlawo and F.A.S. Dairo
Proximate composition, amino acid profile, mineral and the anti-nutrient constituents of ginger root (Zingiber officinale, Roscoe) were determined. Twenty albino rats (Rattus nervegious) of Wistar strain with weight range 185±1.32-222±3.47 g were divided into five groups of four rats each and administered ethanolic extract of ginger root at 100, 200, 300, 400 and 500 mg mL-1 for a period of 28 days. The weight of the rats and the effect on the activities of aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (AKP) and acid phosphatase (ACP) in tissues such as brain, heart, stomach, small intestine, liver, kidney and serum were evaluated. Ginger contained 5.28±0.43% crude protein (CP), 5.54±0.02% ether extract (EE), 5.97±0.04% ash and 66.26±1.03% total carbohydrate with coefficient of variation range 0.01-0.059%. The oxalate content was 4.55±0.07 mg g-1, phytin 28.83±0.73 mg g-1 while tannin was 0.26±0.06%. Phosphorus was 25.70±1.27%, Na, 40.96±1.95%, K, 37.34±1.18%, Ca, 35.66±1.09%, Mn, 19.60±0.62%, Zn, 4.06±1.99%, Fe, 1.44±0.07 and Cu, 0.76±0.07%. Glutamate had the highest amino acid content (11.17±0.22%) while glycine recorded the lowest (1.15±0.06%). Although the body weights of the rats were not significantly (p>0.05) influenced by the administration of ginger root, aspartate transaminase activity significantly increased (p<0.05) at 100 mg mL-1 for the liver (260.56±21.14 μL-1), brain (275.87±18.11 μL-1), kidney (295.24±30.91 μL-1) and serum (104.30±15.03 μL-1). The alanine transaminase activity was significantly highest (p<0.05) at 200 mg mL-1 for the liver (169.38±25.17 μL-1). It was 115.17±19.25 μL-1 for the brain at 400 mg mL-1 and 108.58±20.40 μL-1 for the heart at 300 mg mL-1 dosage. Serum and kidney had their highest (p<0.05) values of 42.37±5.18 and 112.81±13.09 μL-1, respectively on the control group. Alkaline phosphatase had the highest activity (p<0.05) at 400 mg mL-1 (290.32±27.44 μL-1) for the stomach while small intestine recorded 350.62±33.14 μL-1 at 500 mg mL-1 dosage. The brain and serum had 124.55±25.18 μL-1 at 100 mg mL-1 and 160.08±54.15 μ mL-1 at 400 mg mL-1, respectively. Stomach acid phosphatase recorded the highest (p<0.05) activity (163.07±12.04 μL-1) at 500 mg mL-1, small intestine had 198.95±35.27 μL-1 for the control group while serum indicated the highest value of 66.23±6.04 μ mL-1 at 200 mg mL-1 and 164.29±18.23 μ mL-1 at 100 mg mL-1 and at 200 mg mL-1, respectively. The study conclusively showed that ethanolic extract of ginger root did not have any debilitating effect on tissues such as the brain, liver, stomach, small intestine, kidney and the serum.
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How to cite this article

I.G. Adanlawo and F.A.S. Dairo, 2007. Nutrient and Anti-nutrient Constituents of Ginger (Zingiber officinale, Roscoe) and the Influence of its Ethanolic Extract on Some Serum Enzymes in Albino Rats. International Journal of Biological Chemistry, 1: 38-46.

URL: https://scialert.net/abstract/?doi=ijbc.2007.38.46

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