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International Journal of Biological Chemistry
  Year: 2007 | Volume: 1 | Issue: 2 | Page No.: 117-121
DOI: 10.3923/ijbc.2007.117.121
 
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Hypoglycemic and Hepatoprotective Activity of Eugenia jambolana in Streptozotocin-Diabetic Rats

R.Jasmine and P.Daisy

Abstract:
Eugenia jambolana (Myrtaceae) is widely used in traditional system of medicine to treat diabetes in India. The present study was carried out to investigate the effect of methanol extract of E. jambolana on glucose concentrations, serum insulin and liver enzymes in STZ-induced diabetic rats. Oral administration of the methanol extract of E. jambolana (EJ) (150 mg kg-1 b.w.) for 60 days to streptozotocin (STZ) (60 mg kg-1 b.w.)-induced male diabetic wistar rats was able to significantly (p<0.05) decrease the blood glucose concentration and restore normal functioning of liver comparable with the normal rats. Thus, the results of this experimental study shows that Eugenia jambolana possesses hypoglycemic and hepatoprotective effects and is able to ameliorate the diabetic state and is a source of potent hypoglycemic agent.
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How to cite this article:

R.Jasmine and P.Daisy , 2007. Hypoglycemic and Hepatoprotective Activity of Eugenia jambolana in Streptozotocin-Diabetic Rats. International Journal of Biological Chemistry, 1: 117-121.

DOI: 10.3923/ijbc.2007.117.121

URL: https://scialert.net/abstract/?doi=ijbc.2007.117.121

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