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  Year: 2008 | Volume: 7 | Issue: 1 | Page No.: 129-133
DOI: 10.3923/biotech.2008.129.133
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Antimicrobial Activities of the Extracts and Fractions of Allanblackia floribunda

K.K. Ajibesin, N. Rene, D.N. Bala and U.A. Essiett

Allanblackia floribunda is a tree employed in Nigeria and other countries to treat skin disease and other microbial diseases. The ethanol extract, n-hexane, chloroform, ethyl acetate and butanol fractions of the leaves, stem bark and root bark were evaluated for antimicrobial activities against Staphylococcus aureus NCIB 8588, Bacillus subtilis NCIB 3610, Escherichia coli NCIB 86, Proteus vulgaris NCIB 67, Pseudomonas aeruginosa NCIB 950, Klebsiella pneumoniae NCIB 418, Candida albicans and Aspergilus flavus, using agar diffusion method to validate the ethnobotanical uses of the plant. Among the extracts, the ethanol extract of the leaf gave the most significant antibacterial activity. However, no extract showed antifungal activity. Generally, the fractions obtained from the extracts elicited better activity, including antifungal activity against C. albicans. The highest inhibitory effect was exhibited by leaf extract against Ps. aeruginosa NCIB 950, while the ethyl acetate fraction of the stem bark gave the least inhibitory effect against B. subtilis NCIB 3610. The plant extract and fractions produced inhibition zone range between 5 and 35 mm.
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How to cite this article:

K.K. Ajibesin, N. Rene, D.N. Bala and U.A. Essiett, 2008. Antimicrobial Activities of the Extracts and Fractions of Allanblackia floribunda. Biotechnology, 7: 129-133.

DOI: 10.3923/biotech.2008.129.133






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