Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Asian Journal of Plant Sciences
  Year: 2012 | Volume: 11 | Issue: 5 | Page No.: 235-240
DOI: 10.3923/ajps.2012.235.240
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Study of Antioxidant, Analgesic and Antiulcer Potential of Trichosanthes cucumerina Ethanolic Seeds Extract

N.S. Gill, Nistha Marwah, Rashmi Arora and M. Bali

Abstract:
The present study was to investigate antioxidant, analgesic and antiulcer effect of ethanolic seeds extract of Trichosanthes cucumerina. Extraction was done by cold maceration method for 72 h using ethanol as solvent. The preliminary phytochemical screening showed the presence of triterpenoids, flavanoids and sterols. The antioxidant activity was determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging method. The extract showed maximum scavenging activity 86.2% at 150 μg mL-1 by DPPH method as compared to standard antioxidant ascorbic acid. Further extract was studied for antiulcer activity by ethanol induced ulcer model and Non steroidal anti-inflammatory drugs induced method and analgesic activity by Eddy’s hot plate method. Ethanolic extract of Trichosanthes cucumerina cause 72.1 and 57.1% inhibition of ulcer in Non steroidal anti-inflammatory drugs induced model and ethanol induced model at 500 mg kg-1. Result concluded that Ethanolic extract of Trichosanthes cucumerina possess high antiulcer activity which is due to high antioxidant activity and extract also showed potential analgesic activity by Eddy’s hot plate method.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Evaluation of Antioxidant and Antiulcer Activity of Traditionally Consumed Cucumis melo Seeds
  •    Evaluation of Antioxidant and Antiulcer Potential of Cucumis sativum L. Seed Extract in Rats
How to cite this article:

N.S. Gill, Nistha Marwah, Rashmi Arora and M. Bali, 2012. Study of Antioxidant, Analgesic and Antiulcer Potential of Trichosanthes cucumerina Ethanolic Seeds Extract. Asian Journal of Plant Sciences, 11: 235-240.

DOI: 10.3923/ajps.2012.235.240

URL: https://scialert.net/abstract/?doi=ajps.2012.235.240

COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 

Curve Bottom