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Asian Journal of Biological Sciences
  Year: 2018 | Volume: 11 | Issue: 3 | Page No.: 130-137
DOI: 10.3923/ajbs.2018.130.137
 
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Discovery of Antibacterial and Antifungal Activities of South American Vaccinium macrocarpon Fruit: An Ethnomedicinal Plant

Shabana Noreen, Hira Saqib, Ahmad Mukhtar, Umar Shafiq, Muhammad Saad Khan , Tazien Rashid and Ali Qasim

Abstract:
Background and Objective: The antibacterial and antifungal activities of ethnomedicinal plants has been recognized for many years. The leaves of the plant produce many chemical compounds that may be significantly helpful in the defence against various pathogens. In this research, the crude ethanol, n-hexane, chloroform, n-butanol and aqueous soluble extracts of South American Vaccinium macrocarpon was investigated for its antibacterial and antifungal activates against various Gram-positive and Gram-negative pathogens such as Salmonella typhi, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Aspergillus niger. The results were also compared with the conventional medicine such as ciprofloxacin for antibacterial defence while Fluconazole for antifungal defence. Materials and Methods: Two methods were utilized for this purpose, 96-wells microplate method and agar wells diffusion method regarding percentage inhibition, MIC value and zone of inhibitions. Results: The results showed that in antibacterial activities, the first method resulted that n-butanol extract had highest, crude ethanol extract had lowest while n-hexane and chloroform had no antibacterial activities. In the 2nd method the result showed that crude ethanol extract had highest, n-hexane extract had lowest while chloroform had no activities. In the case of antifungal activities, the results of agar wells diffusion method showed that crude ethanol had highest, n-hexane had lowest while chloroform and dimethyl sulfoxide had no antifungal activities. Conclusion: Overall the plant extracts found to be more effective against Gram-negative pathogens than Gram-positive.
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How to cite this article:

Shabana Noreen, Hira Saqib, Ahmad Mukhtar, Umar Shafiq, Muhammad Saad Khan, Tazien Rashid and Ali Qasim, 2018. Discovery of Antibacterial and Antifungal Activities of South American Vaccinium macrocarpon Fruit: An Ethnomedicinal Plant. Asian Journal of Biological Sciences, 11: 130-137.

DOI: 10.3923/ajbs.2018.130.137

URL: https://scialert.net/abstract/?doi=ajbs.2018.130.137

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