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Asian Journal of Biological Sciences

Year: 2013 | Volume: 6 | Issue: 7 | Page No.: 331-339
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Authors

Saeide Saeidi

Parisa Shojaei

Saphora Bazi

Nima Sanadgol

Keywords

Research Article

Antibacterial Activity of Some Iranian Medicinal Plants Against Important Human Pathogens

Saeide Saeidi, Parisa Shojaei, Saphora Bazi and Nima Sanadgol
In order to validate antibacterial properties of five Iranian medicinal plants with respect to traditional uses, we have screened antimicrobial activity of these plants against ten important human pathogenic bacteria. A cross-sectional study was performed Place and Duration of Study: Study performed in Islamic Azad University, Kerman, Iran and Zabol University, Zabol, Iran during 2012 to early 2013. The antimicrobial effect of ethanol, aqueous, Ethyl acetate and chloroform extracts of Marrubium vulgare, Calotorpis procera, Myrtus communis L., Piper nigrum and Cuminum cyminum L. on pathogenic bacteria namely, Pseudomonas aeroginosa, Shigella shinga, Klebsiella pneumoniae, Salmonella typhi, Proteus mirabilis, Serratia marcescens, Bacillus cereus, Enterobacter cloacae, Staphylococcus saprophyticus and Staphylococcus aureus were determined using broth microdiluation method. The results revealed that ethanol and Ethyl acetate was the best extractive solvent in contrast with other solvents for separation of effective components and observation of maximum antimicrobial properties of these plants (p<0.05). Furthermore, P. nigrum and C. cyminum L. were a potent antimicrobial activity respectively against gram-positive (Bacillus cereus) and gram-negative (Proteus mirabilis, Serratia marcescens, Pseudomonas aeroginosa, Enterobacter cloacae) bacteria. The present studies confirm the use of mixes of P. nigrum and C. cyminum L. crude ethanol and Ethyl extracts as widespread antimicrobial agent. Further research is required to evaluate the practical values of therapeutic applications.
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Saeide Saeidi, Parisa Shojaei, Saphora Bazi and Nima Sanadgol, 2013. Antibacterial Activity of Some Iranian Medicinal Plants Against Important Human Pathogens. Asian Journal of Biological Sciences, 6: 331-339.

URL: https://scialert.net/abstract/?doi=ajbs.2013.331.339

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