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Antibacterial Activity of Some Iranian Medicinal Plants Against Important
Human Pathogens |
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Saeide Saeidi,
Parisa Shojaei,
Saphora Bazi and Nima Sanadgol |
Abstract:
In order to validate antibacterial properties of five Iranian medicinal plants
with respect to traditional uses, we have screened antimicrobial activity of
these plants against ten important human pathogenic bacteria. A cross-sectional
study was performed Place and Duration of Study: Study performed in Islamic
Azad University, Kerman, Iran and Zabol University, Zabol, Iran during 2012
to early 2013. The antimicrobial effect of ethanol, aqueous, Ethyl acetate and
chloroform extracts of Marrubium vulgare, Calotorpis procera,
Myrtus communis L., Piper nigrum and Cuminum cyminum L.
on pathogenic bacteria namely, Pseudomonas aeroginosa, Shigella shinga,
Klebsiella pneumoniae, Salmonella typhi, Proteus mirabilis,
Serratia marcescens, Bacillus cereus, Enterobacter cloacae,
Staphylococcus saprophyticus and Staphylococcus aureus were determined
using broth microdiluation method. The results revealed that ethanol and Ethyl
acetate was the best extractive solvent in contrast with other solvents for
separation of effective components and observation of maximum antimicrobial
properties of these plants (p<0.05). Furthermore, P. nigrum and
C. cyminum L. were a potent antimicrobial activity respectively against
gram-positive (Bacillus cereus) and gram-negative (Proteus mirabilis,
Serratia marcescens, Pseudomonas aeroginosa, Enterobacter cloacae)
bacteria. The present studies confirm the use of mixes of P. nigrum and
C. cyminum L. crude ethanol and Ethyl extracts as widespread antimicrobial
agent. Further research is required to evaluate the practical values of therapeutic
applications.
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How to cite this article:
Saeide Saeidi, Parisa Shojaei, Saphora Bazi and Nima Sanadgol, 2013. Antibacterial Activity of Some Iranian Medicinal Plants Against Important
Human Pathogens. Asian Journal of Biological Sciences, 6: 331-339.
URL: https://scialert.net/abstract/?doi=ajbs.2013.331.339
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