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Asian Journal of Biological Sciences
  Year: 2011 | Volume: 4 | Issue: 1 | Page No.: 84-89
DOI: 10.3923/ajbs.2011.84.89
 
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Hypoglycemic Potential of Bridelia retusa Bark in Albino Rats

Anil U. Tatiya, Ujwaldip V. Deore, Pankaj G. Jain and Sanjay J. Surana

Abstract:
In the present study, Bridelia retusa bark was screened for their hypoglycemic potential on normal, oral glucose tolerance study and alloxan induced rats. Albino rats were divided into groups (n = 6) received different treatments consisting of control, methanolic, pet-ether and n-butanol extracts (at a dose of 200 and 400 mg kg-1) and standard drug Glibenclamide (5 mg kg-1 p.o.). Estimation of blood glucose level was done by GOD/POD method. Results indicated that B. retusa extracts does not affect blood glucose level on normal rats but in Alloxan induced diabetic rats n-butanol extract showed significant (p<0.001) fall of blood sugar level. However, the effect of drug was less than standard. Phytochemical analysis has revealed the presence of steroids, triterpenoids, tannins and flavonoids as major constituents.
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How to cite this article:

Anil U. Tatiya, Ujwaldip V. Deore, Pankaj G. Jain and Sanjay J. Surana, 2011. Hypoglycemic Potential of Bridelia retusa Bark in Albino Rats. Asian Journal of Biological Sciences, 4: 84-89.

DOI: 10.3923/ajbs.2011.84.89

URL: https://scialert.net/abstract/?doi=ajbs.2011.84.89

COMMENTS
07 July, 2010
Nikesh D Bari:
i go through this article and i got good references on diabetic . thanks to publish this article
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