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Asian Journal of Biological Sciences
  Year: 2011 | Volume: 4 | Issue: 6 | Page No.: 498-505
DOI: 10.3923/ajbs.2011.498.505
 
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Comparative Study of Some Haematological Parameters in Rats Following Ingestion of Crude Oil (Nigerian Bonny Light), Petrol, Kerosene and Diesel

S.O. Ita and U.A. Udofia

Abstract:
The exposure of Nigerians to crude oil and its refined products is in the increase following incessant oil spills and proliferation of sales outlet. Against this backdrop, comparative effects of Nigerian Bonny Light Crude Oil and some of its refined products (gasoline, kerosene and diesel) on some haematological parameters of male rats of Wister strain were investigated. A total of twenty-five male rats were grouped into five groups, with group 1 serving as control. The remaining four groups were oral gavaged with 6 mL kg-1 body weight of petrol, kerosene, diesel and crude petroleum, respectively. The result obtained showed that Red Blood Cell (RBC), Packed Cell Volume (PCV) and Haemoglobin (Hb) content were significantly lower in petrol (p<0.001), kerosene (p<0.01) and diesel (p<0.05) than the control group. Crude oil also recorded lower values for these parameters which were not statistically different from the control values. Significantly (p<0.05) Mean Corpuscular Volume (MCV) and Mean Corpuscular Haemoglobin (MCH) higher values were recorded for petrol and kerosene groups. Platelets values were significantly higher in all the test groups (p<0.001), than control. White Blood Cell (WBC) was significantly higher in petrol group (p<0.05) but significantly (p<0.01), lower in kerosene diesel and crude petroleum groups. Lymphocytes was significantly (p<0.001) lower in petrol group and recorded marginal reduction in kerosene and diesel but marginal increased in crude petroleum. Neutrophils and eosinophil values were significantly higher (p<0.001) in petrol group and marginally higher in kerosene and diesel groups but marginally lower in crude petroleum group than control group. Values obtained for monocytes in the test groups were not statistically different from the control value. It is, therefore concluded that crude petroleum and some of its products are highly toxic and are potential damaging agents to the haematopoietic system and could cause anaemia, particularly petrol and kerosene when ingested.
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How to cite this article:

S.O. Ita and U.A. Udofia, 2011. Comparative Study of Some Haematological Parameters in Rats Following Ingestion of Crude Oil (Nigerian Bonny Light), Petrol, Kerosene and Diesel. Asian Journal of Biological Sciences, 4: 498-505.

DOI: 10.3923/ajbs.2011.498.505

URL: https://scialert.net/abstract/?doi=ajbs.2011.498.505

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