Review Article

Inhibin: A Role for Fecundity Augmentation in Farm Animals

Anuradha Bhardwaj, Varij Nayan, Parvati, Mamta and A.K. Gupta

Inhibin is a non-steroidal glycoprotein hormone of gonadal origin with major action as negative feedback control of the production of Follicle Stimulating Hormone (FSH) by anterior pituitary gland which in turn modulates male and female reproductive functions. Its physiological role has led to the development of inhibin based immunogens for fertility enhancement in farm animals. It is envisaged that a reduction of endogenous inhibin secretion would increase FSH concentrations and thus offers a potential for increasing the number of ovulatory follicles in the ovary. Immunization against inhibin has been reported to be a useful method for inducing multiple ovulations in farm animals. Inhibins play important roles in the regulation of fertility based on their dual inhibitory action on the process of folliculogenesis in the ovary and FSH secretion by the pituitary. Inhibins are also recognized as paracrine ovarian and testicular regulators and have multiple paracrine effects in the utero-placental unit, representing a promising marker for male and female infertility, gynecological and gestational diseases.

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Anuradha Bhardwaj, Varij Nayan, Parvati, Mamta and A.K. Gupta, 2012. Inhibin: A Role for Fecundity Augmentation in Farm Animals. Asian Journal of Animal and Veterinary Advances, 7: 771-789.

DOI: 10.3923/ajava.2012.771.789

URL: https://scialert.net/abstract/?doi=ajava.2012.771.789

Asian Journal of Animal and Veterinary Advances

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Authors

Anuradha Bhardwaj

Varij Nayan

Parvati

Mamta

A.K. Gupta

Keywords

Review Article

Inhibin: A Role for Fecundity Augmentation in Farm Animals

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