Abstract: Background: The experimental trial was consummated throughout two successive seasons (2014 and 2015) at a commercial orchard at El-Khatatba city, Monifia Governorate, Egypt. It intended to find out the possibility of enhancing Florida prince peach trees productivity under local condition in the newly reclaimed lands by using NPK-humate. Materials and Methods: The NPK-humate in presence or absence of adjuvants (methanol and glycerol) applied as foliar application four times at 2 weeks intervals from the beginning of fruit set after petal fall (18 February) during both seasons to study their effect on vegetative growth, nutrient availability, yield and fruit quality of Florida prince peach trees and the obtained data were statistically analyzed as a randomized complete design by analysis of variance (ANOVA). Results: Data indicated that foliar applications of NPK-humate in presence of adjuvants were better than absence of it, for enhancing peach trees cv. Florida prince production. Conclusion: Specifically, the rate of NPK-humate (1.5%)+methanol (3%) showed the best significant effect on various estimated parameters under this study unless fruit firmness during both seasons. The treatment of NPK-humate at 1.5% with methanol at 3% gave the highest significant values for vegetative growth parameters which reflected positively on yield of peach trees and fruit quality.