Abstract: Information and Communication Technology (ICT), includes a wide range of hardware, software and supportive knowledge that has transformed human society from the information technology age to the knowledge age and dramatically substituted the traditional jobs with newly offered ones. So, the main question that remains to be answered is, whether it could have a positive effect on the level of employment. The present study provides an overview on the effective ways that ICTs help to create more employment opportunities across the selected Organization of Islamic Conference (OIC) economies. For this purpose, an econometric panel data model is run to analyze the relationship between ICT and employment rate of OIC countries for the period 2000 to 2009; using the Constant Elasticity Substitution (CES) category of production function. The results revealed that the introduction of technology has led to major structural changes in the economy of OIC member countries and there is also a positive and significant effect of the ICTs on employment rate but the effects are diversified among oil-based as well as non-oil economies.