Abstract: Phytochemical investigation of the stems of Lecaniodiscus cupanioides Planch (Sapindaceae) afforded two triterpenoid saponins identified as 3-O- [α-L-arabinofuranosyl-(1→3)- α-L-rhamnopyranosyl- (1→2) - α -L-arabinopyranosyl-]-hederagenin (1) and 3-O- [α -L-arabinopyranosyl- (1→3)- α -L-rhamnopyranosyl (1→2)- α -L-arabinopyranosyl-]-hederagenin (2). The structures of the compounds were determined based on chemical investigations and comprehensive NMR spectroscopic studies including 1H, 13C, DEPT, COSY, HMQC, HMBC, MS and comparison with literature data. The compounds exhibited antifungal activity against C. albicans, C. neoformans and A. fumigatus.