Abstract: A combination of social survey and direct field observation was used to identify and determine the conservation status of botanicals used by the indigenous okpe-speaking people of Delta State, Nigeria during natality periods. While a total of 11 botanicals belonging to 11 different families were found to be widely utilized during the pre-natal periods, another 10 botanicals, belonging to 10 different families were widely utilized during the post-natal periods. Only 7 of these botanicals were cultivated. Among the uncultivated botanicals, only 4 were regularly preserved in the study area. Over 40% of the botanicals were sourced from the forest and some of the botanicals were harvested by annihilative extraction methods. Over 40% of the botanicals were presently rare on the abundance scale. Sustainable strategies that could enhance the conservation of these species were proposed.