Abstract: The data on the anatomical properties of wood material is generally preferred and required for the many processes and applications in the wood industry. The main objective of the study was to determine anatomical properties of L. leucocephala wood and to correlate the effects of anatomical properties with oriented strand board properties. The statistical analysis show significant differences in anatomical properties between the age variable. This study revealed that number of vessels per square millimeter in sixteen-year-old wood is higher than eight-year-old wood. Vessels per square millimeter are inversely correlated with vessel width, where with smaller vessel width more vessels per square millimeter are found. Ray width and ray cell were also found to be significantly affected by age. There is no significant difference between number of vessel and tree portion. For vessel width there was no significant different between top and middle portions but shows significant difference with bottom portion. Tree portion was found to affect ray width significantly. Overall, the bottom portion had the bigger ray width. Number of ray cell showed similar trends to effect of vessel width on tree portion. The results of intercorrelation indicated that the effects of the anatomical properties of Leucaena leucocephala on board properties were insignificant except for MOR and MOE in major axis. Generally, the board properties depend on the variation of anatomical properties only for bending properties in major axis.