Abstract: This study presents the results of a study on Acid Mine Drainage (AMD) resources and its remediation in Sarcheshmeh open pit mine, one of the world largest porphyry copper deposits in the southeastern of Iran. Water quality samples were taken from water resources around the Sarcheshmeh mine and from tailing decant water pond. Sarcheshmeh waste dumps are the most important AMD generating sources. Also, Sarcheshmeh tailings decant water acts as a neutralization agent for treating AMD and reduce AMD's metals. Due to the mixing of the tailing decant water with the AMD that reached Sarcheshmeh tailings decant pond by Shur River, Cu, Fe, Mn and Zn concentration reduce around to 99.9, 99.3, 95.9 and 88.92% respect to Shur rive, the source of heavy metals. The reduction ratio for metals is Cu>Fe>Ni>Mn>Zn>Pb>CD>Mg.