HOME JOURNALS CONTACT

Research Journal of Cardiology

Year: 2017 | Volume: 10 | Issue: 1 | Page No.: 1-7
DOI: 10.17311/rjc.2017.1.7
Clinical Application of a Cardiac Diagnostic Method Based on Dynamic Systems Theory
Javier Rodriguez, Signed Prieto, Catalina Correa, Dario Dominguez, Juan Pardo, Fernan Mendoza, Yolanda Soracipa, Nancy Olarte, Diana Margarita Cardona and Laura Mendez

Abstract: Background: A new methodology based on dynamical systems theory has been developed to differentiate normal cardiac dynamic from acute illness by calculating the space occupation of chaotic geometric attractors in the phase space. Objective: The purpose of this study was to apply this methodology to confirm its clinical applicability and the relation between the measures and the appearance of arrhythmic electrical storms. Methodology: There were analyzed 200 holters. The minimum and maximal heart rate and the number of beats per hour were selected. Then, a simulation for constructing the attractor of each cardiac dynamic in the phase space was made. Fractal dimension and space occupation of the attractors with the two grids were calculated according to the box-counting method and the differentiating parameters of normality and acute disease were applied. Sensibility, specificity and kappa coefficient were calculated for evaluating diagnostic concordance. Fractal dimension for normal holters was between 1,621 and 1,970 and between 1,268 and 1,784 for holters with arrhythmic electrical storm. It was not possible to identify differences between groups with mathematical values of fractal dimension. Results: However, space occupation of normal dynamic attractors was always greater than 200 with the 5 beats min–1 grid and space occupation of cases with arrhythmia was between 31 and 60, close to space occupation of cases with acute myocardial infarction, which was between 19 and 23. Conclusion: This study confirmed the clinical applicability of the methodology. It detects when a cardiac dynamic exhibits a progressive diminution of spatial occupation, which is useful to distinguish the cases with arrhythmic electrical storm from cases with chronic arrhythmias or normal dynamic. These findings could be useful to predict appearance of arrhythmic electrical storms.

Fulltext PDF Fulltext HTML

How to cite this article
Javier Rodriguez, Signed Prieto, Catalina Correa, Dario Dominguez, Juan Pardo, Fernan Mendoza, Yolanda Soracipa, Nancy Olarte, Diana Margarita Cardona and Laura Mendez, 2017. Clinical Application of a Cardiac Diagnostic Method Based on Dynamic Systems Theory. Research Journal of Cardiology, 10: 1-7.

© Science Alert. All Rights Reserved