Abstract: The inhibitory effect of extracts from five Jordanian medicinal plants were studied against five plant pathogenic fungi: Crupina crupinastrum, Teucrium polium, Achillea santolina, Micromeria nervosa and Ballota philistaea. All plants showed antifungal activity against the fungi used in this study. The inhibitory effect on activity increased by increasing the concentration (from 100-1000 ppm). The highest growth inhibition of all fungi was found with Achillea santolina at 1000 ppm, which gave 42.2 and 42.0% of inhibition with Fusarium oxysporum and Rhizoctonia solani, respectively and the lowest were Micromeria nervosa and Ballota philistaea which gave 3.6 and 3.5%, respectively against pencillium sp. Results clearly indicate that the medicinal plants were used in this study are a promising source of antifungal compounds.