Abstract: Extract of neem (Azadirachta indica.L) seed was used to control the root knot nematode Meloidogyne javanica of sweet gourd. Extract of neem seed was found to be leathal to the juvenile of M. javanica compared to the extracts of bark and leaf of neem. Pot experiment with standard `S` concentration of all the extracts both in side drench and root-dipping methods appeared to give significant suppression in root galling, L2 and L3 population of the nematode. Identical response among the treatments with respect of plant growth characters was attributed to the synthesis of less toxic metabolites in the immature neem seeds used in the study. Positive correlation between gall number and eggmass indicated higher activity of the nematode allowing more adult females to develop with the production of increased number of eggmasses.