Abstract: Objective: This study was aimed to evaluate the effect of calcium soap-soybean oil on productive and reproductive performances as well as blood profile of Bali cattle. Materials and Methods: This study used 12 heads of Bali cattle with the average body weight of 230 kg at Sobangan Breeding Centre, Bali Province, Indonesia. There were 2 dietary treatments i.e., control (no supplementation of calcium soap-soybean oil) and control+calcium soap-soybean oil 5%. Control diet which consist of Napier grass and concentrate with ratio approximately 80:20 and all treatment diets were offered for 60 days. All cows were oestrous synchronised using PGF2α injections and continued with artificial insemination. Variable measured were feed intake, body weight gain, average daily gain, feed efficiency, service per conception, blood nutrient and haematology. Results: The results showed that the addition of calcium soap-soybean oil significantly increased (p<0.05) feed consumption of forage and concentrate, but slightly decreased body weight gain and feed efficiency compared to the control treatment. Moreover, the addition of calcium soap-soybean oil significantly (p<0.05) enhanced reproductive performance of Bali cows such as pregnancy rate and proportion of cattle with service per conception (S/C) = 1. However, the use of calcium soap-soybean oil did not affect blood metabolites and blood haematology except white blood cells and leucocyte differentiation such as neutrophil, lymphocytes and monocyte. Conclusion: The use of calcium soap-soybean oil has positive effect on reproductive performance without altering the health status of Bali cows.