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Pakistan Journal of Nutrition

Year: 2017 | Volume: 16 | Issue: 5 | Page No.: 364-371
DOI: 10.3923/pjn.2017.364.371
Phenotype Development of Long Tailed Monkey (Macaca fascicularis) Fed Obese Diet
Deyv Pijoh, Sri Supraptini Mansjoer, Dondin Sajuthi, Dewi Apri Astuti and Irma Herawati Suparto

Abstract: Objective: This study was conducted to develop an animal model of obesity by monitoring the phenotypes of long-tailed monkeys (Macaca fascicularis) fed a high energy diet. Methodology: Fifteen adult male Long-Tailed Monkeys (LTM) weighing between 4 and 5 kg were divided into three groups of five that received one of three diets: Diet A: A commercial monkey chow diet, Diet B: Monkey chow supplemented with egg yolk and Diet C: In which wheat was the main ingredient and beef tallow was added. Body measurements, including body weight were collected monthly. Results: The LTM fed Diet B (Egg yolk-supplemented) consumed more food compared to those fed Diet A and C. Animals in the Diet B group had significantly (p<0.01) larger waist circumference, hip circumference, chest circumference and skin fold thickness compared to the other two groups. There was a close relationship between body weight and waist circumference (r = 0.863), chest circumference (r = 0.889) and hip circumference (r = 0.890). Based on the main component analysis, LTM fed Diet B had higher rates of obesity compared to LTM fed Diet A or C. Conclusion: Body characteristics of LTM fed different diets can be used to determine the presence of obesity. The LTM can serve as a useful animal model of obesity and findings from this model can be applied to studies of obesity in humans.

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How to cite this article
Deyv Pijoh, Sri Supraptini Mansjoer, Dondin Sajuthi, Dewi Apri Astuti and Irma Herawati Suparto, 2017. Phenotype Development of Long Tailed Monkey (Macaca fascicularis) Fed Obese Diet. Pakistan Journal of Nutrition, 16: 364-371.

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