Abstract: Tapinanthus bangwensis (African Mistletoe), leaf meal was used as a replacement for GNC at 0, 5, 10 and 15% levels of inclusion in broiler diets. One hundred and twenty day-old (Anak strain) broiler chicks were used for the study which lasted for six weeks. Feed intake and body weight gain were determined weekly. The feed/gain and gain/feed ratios were also determined. At the end of the study five birds per treatment were randomly selected, starved and bled for blood samples to be used for haematological and serum chemistry. There was no significant difference (p>0.05) in feed intake, but there was (p<0.05) in body weight gain. Statistical analysis showed significant difference (p<0.05) in haemoglobin, PCV and RBC; but no significant difference (p>0.05) in WBC. The serum parameters showed no significant difference (p>0.05) among treatment means except in globulin. Treatment IV showed the least feed cost/kg feed. No mortality was recorded throughout the feeding trial.