Abstract: This paper reports a study on mice and human to check the theory of Stolkowski which hypothesizes that mineral (Na, K, Ca) imbalance in the diet of the female before fertilization affects the sex ratio of the progeny. For this aim, total 40 female and 16 male 2 months age white mice used; which were separated into 8 groups, each of them consisted of 5 female and 2 male animals. Group 1 was a control, group 2-3-4-5-6-7 and 8 were treated as experimental groups. (0.5 g Na/kg feed, 2,0 g K/kg feed and 5,0 g Ca/kg feed); feed was given to group 1 while group 2-3-4-5-6-7 and 8 received in their feed 1.5 g Na/kg feed, 6,0 g K/kg feed and 15,0 g Ca/kg feed during 30 days before mating. K had the highest male ratio in their litter followed by those given Ca+K. Population of Canakkale was evaluated by traditional nutrition of habits and no found statistical differences in sex both m/f (P>0.10).