Abstract: Background and Objective: Maize cultivation technology package development is a solution in increasing maize production, especially prolific maize. However, technology package evaluation has to be evaluated with interaction towards crop genetics. The purpose of this research is to discover the interaction between maize variety towards cultivation technology (plant fertilization and spacing) and to find information about secondary production characters in cultivation technique optimization. Materials and Methods: This research used a split-split-plot design. The main plot was planting system (S) consisted of three planting systems. Sub Plot (SP) was fertilizing plans ha–1 (P) consisted of four plans. Whereas Sub-Sub Plot (SSP) were (V): NASA 29 (V1), Bisi 2 (V2) and Sinha's 1 (V3). There were 15 characters observed. Results: The results prolific potential is very dynamic which is determined by genetic potential, cultivation technology and genetic-cultivation technology interactions. The increase in the prolific potential will have a direct effect on increasing maize productivity. In general, the use of legowo lines and Eco-farming (biofertilizer) can increase prolific potential and productivity. Conclusion: According to this research, the prolific potential is highly dynamic which is determined by genetic potential, cultivation technology and genetic-cultivation interaction. Technology considered in increasing maize productivity is Legowo plant spacing (50+100)×20 cm combined with N:P:K = 200:100:50+KNO3 25 kg ha–1+Eco farming 5 cc L–1. This technique combination is recommended in maize productivity increase.