Abstract: The present study was designed to measure the monthly and seasonal variation in the lipid and carbohydrate content of Schizothorax esocinus. Total lipid content of the fish was measured by Folch,s method and the carbohydrate content was evaluated by Dubois method. The lipid content of Schizothorax esocinus varied seasonally, with maxima and minima in a year. The highest lipid content (0.45 g g-1) was measured in the July and the lowest lipid content (0.25 g g-1) in November. Evaluating the proximate composition of fish is important aspect in fish nutrition. The carbohydrate does not vary so much with a slight increase in spring (0.18%) and a slight decrease in autumn season (0.10%) with an average value of 0.14%.Total protein profile was also carried out in different organs of the fish by using SDS PAGE. The fish is a good source of lipid, carbohydrate and proteins, required for the balanced diet of human consumption.