Abstract: The proximate, minerals and amino acids contents of wild melon (Citrullus ecirrhosus) seeds were determined. The results for proximate analysis (% DW) showed a composition of 3.73±0.25 moisture, 2.12±0.08 ash 26.36±0.10 crude protein, 50.67±0.76 crude lipid, 2.17±0.29 crude fibre, 18.69±0.82 available carbohydrate and energy value of 601.7±8.75 kcal/ 100 g. The seeds amino acids profile revealed that for adults but leucine, lysine and threonine are below the requirement value for children. The overall result implies that seed of the wild melon possessed the potential to be used as a source of nutrition.