Abstract: The ethanol leaf extract of Cymbidium aloifolium (L.) was evaluated for its analgesic and anti-inflammatory activities. The extract, at the dose of 200 and 400 mg kg-1 body weight, exerted the analgesic activity by observing the number of abdominal contractions and anti-inflammatory activity against Carrageenin induced paw edema in mice by measuring the paw volume. The ethanolic extract of Cymbidium aloifolium (L.) showed statistically significant (p<0.05) reduction of percentage of writhing of 33.57 and 61.31% at 200 and 400 mg kg-1 oral dose, respectively, when compared to negative control. The Ethanolic plant extract also showed significant (p<0.05) dose dependent reduction of mean increase of formation of paw edema. The results of the experiment and its statistical analysis showed that the ethanolic plant extract had shown significant (p<0.05) dose dependent analgesic and anti-inflammatory activities when compared to the control.