Abstract: In current study, it reported the synthesis of water soluble; monos disperse Al/Au bimetallic nanoparticles with a middling length of 7 nm. Synthesis engages concurrent reduction of Al3+ and Au3+ in water to give way bimetallic nanoparticles. The elemental content of Al is 1.5%. Nanoparticles display ferromagnetic performance as deliberate by SQUID. These particles can be effortlessly conjugated to thiolated DNA, as confirmation by mobility shifts in agarose gel electrophoresis. Nanoparticles heat in solution to temperatures above 40°C, representative appropriateness for hyperthermia.