Abstract: The aim of this study was to evaluate mental health status in caregivers of patients with chronic psychiatric disorders. This descriptive-analytic study performed in Mazandaran Province Northern Iran from 2007 to 2008. Two hundred caregivers of patients with sever psychiatric disorders completed (GHQ-28) and Demographic questionnaire. Sever psychiatric disorders is referred to patients with schizoaffective or schizophrenia or bipolar mood disorder that at least 2 years was passed from onset of disease. Data were analyzed in descriptive statistical method with SPSS soft ware. Thirty five percent of caregivers had GHQ>23 and no mental health. Significant association found between patients age, age of onset of disease with GHQ Score (p = 0.0001). Caregivers' GHQ score correlated with marital status in patients, although this was not significant (p = 0.08). The χ2 test didn't show significant relationship between duration and type of disease and patient's sex and caregiver's sex with GHQ score. According to the results of our study, it seems that further investigations with more samples and other questionnaires need to evaluate of caregivers requirements and it is suggested that a logical planning be conducted by the authorities, to decrease caregivers' burden.