Abstract: In this study, structure, size and distribution of nephron cells on kidney in Huso huso were investigated. The head, body and caudal part of kidney in juvenile Huso huso were sampled. The kidney of Huso huso consisted of glomerulus, proximal, distal and collecting tubule cells. The average area in 1 and 2 year old sturgeon were 2718.07±1387.51 and 2793.89±1348 μm in proximal cells, 2678.80±1249.12 and 2599.98±1428.13 μm in distal cells, 2275.44±1289.52 and 2312.23±1629.58 μm in collecting tubule cells, 4359.8±1573.59 and 5071.04±1916.87 μm in glomerulus and 6019.68±1800.55 and 8307.49±2073.53 μm in Bowman`s capsule, respectively. Average long and small diameter in 1 and 2 year were 68.03±17.82 and 49.94±12.73, 63.29±16.15 and 45.58±12.46 μm in proximal cells, 63.25±16.01 and 44.3±15.09, 63.514±15.25 and 45.46±13.3 μm in distal cells, 51.9±13.04 and 40.54±12.21, 57.08±16.7 and 45.53±15.28 μm in the collecting tubule cells, 91.18±17.93 and 68.72±16.22, 98.7±21.85 and 72.24±17.48 μm in glomerulus and 99.32±19.82 and 76.45±1896, 125.44±24.93 and 93.85±24.78 μm in Bowman`s capsule, respectively. In all cases no statistically significant difference detected in the measured cells among 1 and 2 year old fishes. Morpho-histological pattern of kidney can be developed on the basis of size, feature and distribution of cells in farmed Sturgeon.