Abstract: The nutritional composition such as moisture, ash, lipid protein, carbohydrate, total chlorophyll, crude fibre, phenol, β-carotene, vitamin-B1, vitamin-B2, vitamin-C, Calcium, phosphorus and iron content of four varieties of healthy and Phyllectinia corylea infected mulberry leaves at mature stage has been analyzed. The mulberry leaves are considered as a good sources of starch, protein, crude fibre, minerals, vitamin-C, β-carotene and were estimated about 6-7, 4.0-4.6, .0, .0-3.5, 15-132, 00-120 mg%, respectively. Moisture, ash, lipid, crude fibre, carbohydrate, vitamins and minerals content were decreased significantly but protein and phenol content were increased after infected of mulberry leaves with fungus, Phyllectinia corylea.