Abstract: The cytogenetics effects of Logran, active substance Triasulfuron, at different concentrations, sex and application periods were investigated on bone marrow chromosomes in mice. Male and female mice were applied intraperitonally with 125, 250 and 500 μg mL-1 concentrations of Logran for 12 and 24 h. Logran induced chromosome aberrations like chromatid gap, isochromatid gap, chromatid break, isochromatid break and centromeric attenuation on bone marrow cells of mice. Increase of chromosomal aberration reduced mitotic activity. According to the our study, Logran is genotoxic on bone marrow cells of Mus musculus.