Abstract: The present study was carried out in order to investigate the lesions in the abomasum of Makoyee breed sheep caused by Teladorsagia spp. Infected sheep which were examined during spring and summer 2000, subjected to detail necropsy with special reference to abomasal lesions. Six out of 20 sheep were infected with T. circumcincta. Abomasal changes were recorded and tissue samples were collected from abomasum for histopathology. The results were indicated different pathological changes such as congestion of blood vessels, oedema, foci of T. circumcincta in the superficial part of mucosa, sometimes deep in the glandular region and increased mucous secretion. Also, cystic spaces were found in some glands and infiltration of leukocytes in the mucosa, submucosa and muscular layers were seen. The other findings were hyperplasia of glands, muscular layer of the abomasum and thickening of blood vessel walls. This study brought to light the significant pathological changes even in the light infection caused by T. circumcincta in the abomasum of Makoyee breed sheep.