Abstract: A six weeks old native kid from a flock with history of diarrhea with or without mucus or blood, unthriftness, emaciation, weakness, anorexia and death was referred to Department of Pathobiology, Faculty of Veterinary Medicine, University of Shiraz. At necropsy, severe and diffuse white nodular lesions were present on the mucosal surface of jejunum. The direct smear of mucosal scrapings showed large number of oval oocysts. Histopatological examination of jejunal nodules revealed severe hyperplasia of the villous and crypt epithelial cells containing developmental stages of Eimeria species. In lesions exhibiting this hyperplasia, elongated crypts and long papillary fronds of villi were observed. In addition, very long extensions of tunica submucosa were seen between adenomatous mucosal surface. Gross and histopathological examination of jejunum is very important in post mortem diagnosis of intestinal coccidiosis in goats. In our study, macroscopic and microscopic lesions of coccidiosis in the jejunum were unique and very severe.