Abstract: Intra-specific variation in water-soluble carbohydrates (WSC), reducing sugar (RS), photosynthetic pigments and free proline were determined in sixth leaves and roots of two cultivars salt-tolerant (Karchia) and salt-sensitive (Ghods) of wheat (Triticum aestivum) grown in a greenhouse under controlled condition. Plants were irrigated with various levels of salt (0, 75, 150 and 225 mM NaCl) and sprayed with 0, 30, 60 and 90 ppm of paclobutrazol (PBZ) solution. WSC and RS in leaves and RS in roots increased in line with elevating of salinity from 75 to 225 mM of NaCl in both cultivars. A highly significant increase in RS was observed in leaves of cultivar Ghods at level 225 mM NaCl. PBZ treatment increased WSC and RS in leaves and RS in roots in both cultivars, but reduced RS in leaves in cultivar Ghods. Salt stress decreased photosynthesis pigments, significantly in cultivar Ghods, but PBZ treatment increased photosynthesis pigments in plants irrigated with NaCl solution or without. Salt stress and PBZ treatment increased free proline content, but the most significant increase was observed at level 225 mM of NaCl in cultivar Ghods. It may be concluded that PBZ could enhance salt tolerance with increasing osmoprotectants especially in salt-sensitive cultivar.