Abstract: The study was conducted to determine the profitability of alternate rice-fish culture from the viewpoint of small, medium and large farmers. In total 80 alternate rice-fish producing farmers in which 24 small, 44 medium and 12 large farmers were purposively selected from each of the selected strata from three villages under Bhaluka Upazila of Mymensingh district for the study. The study showed that the alternate rice-fish culture was a profitable business. Per hectare costs of alternate rice-fish culture were Tk 46656.25, 47079.26 and 54268.74 for small, medium and large farms, respectively. Per hectare yield of fish, under small, medium and large farms were 1123.85, 1076.92 and 1179.80 kg, respectively and their corresponding yields of rice were 4323, 4491 and 4512 Kg. The average per hectare net returns from alternate rice-fish culture were Tk 27463.50, 28226.33 and 31018.61 for the small, medium and large farms, respectively.